Aprilaire and Compatible Air Filters by SpiroPure

All Filters stocks a full range of Aprilaire compatible air filters by SpiroPure alongside genuine OEM options, organized by cabinet size and part number for easy lookup. Aprilaire air cleaner cabinets use deep-media formats in several standard sizes, most commonly 16x25x3, 16x25x5, and 20x25x5, and SpiroPure produces compatible replacement media for each. Select your cabinet size to compare Aprilaire OEM and SpiroPure options side by side, with pricing, MERV ratings, and replacement intervals clearly listed.

Aprilaire / Space-Gard Air Cleaner Filters
Aprilaire / Space-Gard

OEM Brand

OEM Part Number

Nominal Size

Filter Options


Aprilaire / Space-Gard

410

16x25x4

SELECT

413

16x25x4

SELECT

401

16x27x6

SELECT

501

16x27x6

SELECT

210

20x25x4

SELECT

213

20x25x4

SELECT

201

20x25x6

SELECT

261

21x24x6

SELECT

SpiroPure Compatible Filters for Aprilaire Cabinets

SpiroPure compatible filters for Aprilaire cabinets are manufactured to match OEM nominal dimensions and media specifications, ensuring proper fit and consistent airflow. The primary advantage is cost: SpiroPure compatible filters are typically priced significantly lower than genuine Aprilaire media, making them a practical choice for homeowners on a regular annual replacement schedule. MERV 8 and MERV 11 options are available for most Aprilaire cabinet sizes. If you prefer genuine Aprilaire OEM filters including the 410, 413, 201, 210, 213, or 401, those are available through the Aprilaire OEM page at All Filters.

FAQs on SpiroPure Air Filters for Aprilaire

Are SpiroPure filters compatible with Aprilaire air cleaner cabinets?

Yes. SpiroPure produces compatible replacement filters for the most common Aprilaire cabinet sizes including 16x25x4 and 16x27x6. Filters are matched by nominal size and actual dimensions to seat properly in Aprilaire filter housings.
SpiroPure compatible filters use pleated media construction and MERV rating standards consistent with OEM specifications. The main difference is price. SpiroPure filters are typically priced lower than genuine Aprilaire media such as the 410 or 413, making them a practical option for budget-conscious homeowners.
For most households, MERV 11 provides a strong balance of allergen capture and airflow. MERV 8 is a solid baseline for homes without significant allergy concerns. Check your Aprilaire cabinet documentation before upgrading to MERV 13, as not all cabinets are rated for higher restriction media.
Deep-media Aprilaire cabinet filters including SpiroPure compatible options in the 4-inch and 6-inch formats typically last 6 to 12 months under normal residential conditions. Households with multiple pets, high allergy sensitivity, or heavy system runtime should replace closer to the 6-month mark.
Yes. SpiroPure filters are available in multi-packs to reduce per-filter cost compared to retail and ensure you always have a replacement on hand. All Filters also offers email replacement reminders so you never miss a filter change. Free shipping applies to orders over $99.